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Technische Universität München
Picture of Jan Jakob Wilkens

Univ.-Prof. Dr. Jan Jakob Wilkens

Technical University of Munich

Former TUM Department of Medicine

Postal address

Ismaninger Straße 22
81675 München

  • Medical Radiation Physics
  • Radiation Therapy with Photons and Particles
  • Laser-driven Ion Beams
  • Treatment Planning, Dose Calculation and Optimization
  • Medical Imaging

  • 28Florian T. Gassert Rico Burkhardt Thomas Gora Daniela Pfeiffer Alexander A. Fingerle Andreas P. Sauter Daniela Schilling Ernst J. Rummeny Thomas E. Schmid Stephanie E. Combs Jan J. Wilkens Franz Pfeiffer: X-ray Dark-Field CT for Early Detection of Radiation-induced Lung Injury in a Murine Model. Radiology , 2022 mehr… BibTeX Volltext ( DOI )
  • 27Burkhardt, Rico; Gora, Thomas; Fingerle, Alexander A.; Sauter, Andreas P.; Meurer, Felix; Gassert, Florian T.; Dobiasch, Sophie; Schilling, Daniela; Feuchtinger, Annette; Walch, Axel K.; Multhoff, Gabriele; Herzen, Julia; Noël, Peter B.; Rummeny, Ernst J.; Combs, Stephanie E.; Schmid, Thomas E.; Pfeiffer, Franz; Wilkens, Jan J.: In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice. Physics and Imaging in Radiation Oncology 20, 2021, 11-16 mehr… BibTeX Volltext ( DOI )
  • 26Burkhardt, Rico; Gora, Thomas; Fingerle, Alexander A.; Sauter, Andreas P.; Meurer, Felix; Umkehrer, Stephan; von Teuffenbach, Maximilian; Kampfer, Severin; Schilling, Daniela; Feuchtinger, Annette; Walch, Axel K.; Rummeny, Ernst; Combs, Stephanie E.; Schmid, Thomas E.; Pfeiffer, Franz; Wilkens, Jan J.; Herzen, Julia: Early detection of radiation-induced lung damage with X-ray dark-field radiography in mice. European Radiology, 2020 mehr… BibTeX Volltext ( DOI )
  • 25Burger, Karin; Urban, Theresa; Dombrowsky, Annique C.; Dierolf, Martin; Günther, Benedikt; Bartzsch, Stefan; Achterhold, Klaus; Combs, Stephanie E.; Schmid, Thomas E.; Wilkens, Jan J.; Pfeiffer, Franz: Technical and dosimetric realization of in‐vivo X‐ray microbeam irradiations at the Munich Compact Light Source. Medical Physics 47 (10), 2020, 5183-5193 mehr… BibTeX Volltext ( DOI )
  • 24Dombrowsky, Annique C.; Burger, Karin; Porth, Ann-Kristin; Stein, Marlon; Dierolf, Martin; Günther, Benedikt; Achterhold, Klaus; Gleich, Bernhard; Feuchtinger, Annette; Bartzsch, Stefan; Beyreuther, Elke; Combs, Stephanie E.; Pfeiffer, Franz; Wilkens, Jan J.; Schmid, Thomas E.: A proof of principle experiment for microbeam radiation therapy at the Munich compact light source. Radiation and Environmental Biophysics 59, 2020, 111–120 mehr… BibTeX Volltext ( DOI )
  • 23Eggl, Elena; Grandl, Susanne; Sztrόkay-Gaul, Anikό; Dierolf, Martin; Jud, Christoph; Heck, Lisa; Burger, Karin; Günther, Benedikt; Achterhold, Klaus; Mayr, Doris; Wilkens, Jan J.; Auweter, Sigrid D.; Gleich, Bernhard; Hellerhoff, Karin; Reiser, Maximilian F.; Pfeiffer, Franz; Herzen, Julia: Dose-compatible grating-based phase-contrast mammography on mastectomy specimens using a compact synchrotron source. Scientific Reports 8 (1), 2018, 15700 mehr… BibTeX Volltext ( DOI )
  • 22Mei, Kai; Ehn, Sebastian; Oechsner, Markus; Kopp, Felix K.; Pfeiffer, Daniela; Fingerle, Alexander A.; Pfeiffer, Franz; Combs, Stephanie E.; Wilkens, Jan J.; Rummeny, Ernst J.; Noël, Peter B.: Dual-layer spectral computed tomography: measuring relative electron density. European Radiology Experimental 2 (1), 2018 mehr… BibTeX Volltext ( DOI )
  • 21Burger, Karin; Ilicic, Katarina; Dierolf, Martin; Günther, Benedikt; Walsh, Dietrich W. M.; Schmid, Ernst; Eggl, Elena; Achterhold, Klaus; Gleich, Bernhard; Combs, Stephanie E.; Molls, Michael; Schmid, Thomas E.; Pfeiffer, Franz; Wilkens, Jan J.: Increased cell survival and cytogenetic integrity by spatial dose redistribution at a compact synchrotron X-ray source. PLOS ONE 12 (10), 2017, e0186005 mehr… BibTeX Volltext ( DOI )
  • 20Falkinger, Marita; Schell, Stefan; Müller, Johannes; Wilkens, Jan J.: Prioritized optimization in intensity modulated proton therapy. Zeitschrift für Medizinische Physik 22, 2012, 21-28 mehr… BibTeX Volltext ( DOI )
  • 19Greubel, Christoph; Assmann, Walter; Burgdorf, Christian; Dollinger, Günther; Du, Guanghua; Hable, Volker; Hapfelmeier, Alexander; Hertenberger, Ralf; Kneschaurek, Peter; Michalski, Dörte; Molls, Michael; Reinhardt, Sabine; Röper, Barbara; Schell, Stefan; Schmid, Thomas E.; Siebenwirth, Christian; Wenzl, Tatiana; Zlobinskaya, Olga; Wilkens, Jan J.: Scanning irradiation device for mice in vivo with pulsed and continuous proton beams. Radiat Environ Biophys 50, 2011, 339-344 mehr… BibTeX Volltext ( DOI )
  • 18Frese, Malte C.; Wilkens, Jan J.; Huber, Peter E.; Jensen, Alexandra D.; Oelfke, Uwe; Taheri-Kadkhoda, Zahra: Application of Constant vs. Variable Relative Biological Effectiveness in Treatment Planning of Intensity-Modulated Proton Therapy. International Journal of Radiation Oncology*Biology*Physics 79, 2011, 80-88 mehr… BibTeX Volltext ( DOI )
  • 17Wenzl, Tatiana; Wilkens, Jan J: Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications. Radiation Oncology, 2011, 171 mehr… BibTeX Volltext ( DOI )
  • 16Kampfer, Severin; Schell, Stefan; Duma, Marciana N; Wilkens, Jan J; Kneschaurek, Peter: Measurements to predict the time of target replacement of a helical tomotherapy. Journal of Applied Clinical Medical Physics 12 (4), 2011 mehr… BibTeX
  • 15Wenzl, Tatiana; Wilkens, Jan J: Modelling of the oxygen enhancement ratio for ion beam radiation therapy. Physics in Medicine and Biology 56 (11), 2011, 3251 mehr… BibTeX
  • 14Duma, Marciana Nona; Kampfer, Severin; Wilkens, Jan Jakob; Schuster, Tibor; Molls, Michael; Geinitz, Hans: Comparative Analysis of an Image-Guided Versus a Non–Image-Guided Setup Approach in Terms of Delivered Dose to the Parotid Glands in Head-and-Neck Cancer IMRT. International Journal of Radiation Oncology*Biology*Physics 77, 2010, 1266-1273 mehr… BibTeX Volltext ( DOI )
  • 13Schell, Stefan; Wilkens, Jan J.: Advanced treatment planning methods for efficient radiation therapy with laser accelerated proton and ion beams. Med. Phys. 37 (10), 2010, 5330 mehr… BibTeX Volltext ( DOI )
  • 12Pflugfelder, Daniel; Wilkens, Jan J.; Nill, Simeon; Oelfke, Uwe: A comparison of three optimization algorithms for intensity modulated radiation therapy. Zeitschrift für Medizinische Physik 18, 2008, 111-119 mehr… BibTeX Volltext ( DOI )
  • 11Wilkens, Jan J.; Oelfke, Uwe: Direct Comparison of Biologically Optimized Spread-out Bragg Peaks for Protons and Carbon Ions. International Journal of Radiation Oncology*Biology*Physics 70, 2008, 262-266 mehr… BibTeX Volltext ( DOI )
  • 10Taheri-Kadkhoda, Zahra; Björk-Eriksson, Thomas; Nill, Simeon; Wilkens, Jan J; Oelfke, Uwe; Johansson, Karl-Axel; Huber, Peter E; Münter, Marc W: Intensity-modulated radiotherapy of nasopharyngeal carcinoma: a comparative treatment planning study of photons and protons. Radiation Oncology, 2008, 4 mehr… BibTeX Volltext ( DOI )
  • 9Kang, Joanne H; Wilkens, Jan J; Oelfke, Uwe: Non-uniform depth scanning for proton therapy systems employing active energy variation. Physics in Medicine and Biology 53 (9), 2008, N149 mehr… BibTeX
  • 8Ziegenhein, Peter; Wilkens, Jan J; Nill, Simeon; Ludwig, Thomas; Oelfke, Uwe: Speed optimized influence matrix processing in inverse treatment planning tools. Physics in Medicine and Biology 53 (9), 2008, N157 mehr… BibTeX
  • 7Kang, Joanne H.; Wilkens, Jan J.; Oelfke, Uwe: Demonstration of scan path optimization in proton therapy. Med. Phys. 34, 2007, 3457 mehr… BibTeX Volltext ( DOI )
  • 6Wilkens, Jan J; Alaly, James R; Zakarian, Konstantin; Thorstad, Wade L; Deasy, Joseph O: IMRT treatment planning based on prioritizing prescription goals. Physics in Medicine and Biology 52 (6), 2007, 1675 mehr… BibTeX
  • 5Wilkens, Jan J; Oelfke, Uwe: Fast multifield optimization of the biological effect in ion therapy. Physics in Medicine and Biology 51 (12), 2006, 3127 mehr… BibTeX
  • 4Wilkens, Jan J.; Oelfke, Uwe: Optimization of radiobiological effects in intensity modulated proton therapy. Med. Phys. 32, 2005, 455 mehr… BibTeX Volltext ( DOI )
  • 3Wilkens, Jan J.; Oelfke, Uwe: Three-dimensional LET calculations for treatment planning of proton therapy. Zeitschrift für Medizinische Physik 14, 2004, 41-46 mehr… BibTeX Volltext ( DOI )
  • 2Wilkens, Jan J.; Oelfke, Uwe: Analytical linear energy transfer calculations for proton therapy. Med. Phys. 30, 2003, 806 mehr… BibTeX Volltext ( DOI )
  • 1Karin Burger, Katarina Ilicic, Martin Dierolf, Benedikt Günther, Dietrich W. M. Walsh, Ernst Schmid, Elena Eggl, Klaus Achterhold, Bernhard Gleich, Stephanie E. Combs, Michael Molls, Thomas E. Schmid, Franz Pfeiffer, Jan J. Wilkens: Study of microbeam radiation therapy in-vitro at the Munich Compact Light Source. (anderer Eintrag) mehr… BibTeX Volltext ( DOI )

2012

Head of the Medical Physics Unit within the Department of Radiation Oncology, Klinikum rechts der Isar TUM (Germany)
2008 Professor for “Advanced Technologies in Radiation Therapy”, Technische Universität München (Germany)
2006 Post Doctoral Research Associate at Washington University in St. Louis (USA)
2004 - 2008 Research Associate at the German Cancer Research Center (DKFZ) in Heidelberg (Germany)
2003 Research Fellow at Massachusetts General Hospital, North-East Proton Therapy Center (NPTC), Boston (USA)
2001 - 2004 PhD thesis at the German Cancer Research Center (DKFZ) and the University of Heidelberg (Germany)
2000 - 2002 Studies of Medical Physics and Engineering, University of Kaiserslautern (Germany)
1995 - 2001 Studies of Physics, Universities of Munich (Germany) and Nottingham (UK)
1974 Born in Munich (Germany)
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